Cheapest Cialis 20 mg

buy cialis 20 mg

Have you ever had troubles in the bedroom? Have you ever been scared of running into sexual problems in the future? Have you ever thought that this is fiasco and there is no solution? If so, you were mistaken. Cialis is the drug, which leaves sexual dysfunction in the past. Millions of men all over the world have already experienced all the benefits of this unique medication on themselves. They estimate Cialis as an excellent remedy that has given them the second chance and provided full sexual life and happy relationship with the partner. Do you still doubt? This article is specially for you. 

Description

Cialis (the main active ingredient is tadalafil) was first discovered in 1991 as PDE5 inhibitor. It had three periods of testing in 1993, 1995, and 1997 on men who suffered from erectile dysfunction. In 2003, it was approved by FDA as a remedy to combat ED, and 2011 it also got FDA approval for benign prostatic hyperplasia treatment (the state when prostate gland enlarges, causing problems with urination, such as urgent, difficult, frequent urination, especially at night, and a weak stream of urine). 

Cialis is also approved in the USA, Canada and Japan as a medication for patients with pulmonary arterial hypertension (the state when the vessels in the lungs are narrowed, and the blood flow in the lung arteria is problematic, that causes higher blood pressure and leads to cardiac insufficiency). The official producer and distributor of Cialis is Lilly ICOS, LLC. In 2016, according to the statistics, Cialis was on the 280th place by importance and purchasing power in the USA among other 1,5 million medications.

Brand Cialis is available in any drug store, but it is rather expensive. Generic versions of Cialis, mostly produced in India, are much cheaper, but of the same quality and effect. They have the same active ingredient tadalafil, and are approved for use. You can buy them from internet retailers. The consultation with your doctor is highly recommended, but if you do not want to disclose your personal details, you can buy generics anonymously. Moreover, you will not have to overpay within the framework of the current health insurance.

Cialis 20 mg is available in the form of almond shape big dark yellow tablets in the packages of 4, 8, 12, 16 and 28 pills in each. The sign C20 on each tablet will show that you have got the dosage you wanted. Cialis 20 mg is meant for use on demand and for the case if the smaller dosage 10 mg did not work properly. The dosage 20 mg is considered to be rather high. The effect of the drug lasts up to 36 hours.

You should remember that tadalafil facilitates chemical processes in the body that lead to the erection, but it will not work without any sexually stimulation. Cialis is not suitable for recreation purpose. The pill should be taken orally with a glass of water at least half an hour before planned sexual contact. It doesn’t matter if you take it before or after a meal, but better avoid eating too fatty food, as it can slow down tadalafil performance. It is not allowed to take more than one pill a day, as it has a long period of action in the body, its half-life is 18 hours. This way Cialis (tadalafil) wins against Viagra (sildenafil), and Levitra (vardenafil), which act in the body four or five hours only.

Mechanism of Action

While sexual stimulation of penis, nitric oxide releases from nervous and endothelial cells, and enters the blood flow. It leads to cGMP synthesis in the smooth muscles. Cyclic guanosine monophosphate relaxes penis arteries and increases blood flow into it. This process ends in erection. Tadalafil is one of PDE5 inhibitors. Phosphodiesterase type 5 is an enzyme, which disrupts cGMP and prevents good and stable erection. Inhibiting PDE5, Cialis combats erectile dysfunction.

Three most popular PDE5 inhibitors sildenafil and vardenafil, tadalafil have similar way of action, and along with PDE5, they also inhibit other PDE enzymes. Tadalafil inhibits PDE6 and PDE1, which are found in the eyes, brain, and heart, less than sildenafil and vardenafil, so its users have less adverse reactions, such as increased sensitivity to light, vasodilatation, tachycardia, or flushing. Tadalafil inhibits PDE11 enzyme, which works in the bones, prostate, liver, kidneys, etc., more than other drugs, but it is unknown if this influences the skeleton muscles and other organs. Practice shows that in the whole tadalafil is milder than two other medications.

Side Effects

In a clinical research, the group of men aged from 22 up to 88 years old (middle age 56 years old) took tadalafil 10 mg and 20 mg during 3 months. The research showed that 3.1% of patients had to stop the treatment because they had adverse reactions.

Most common negative consequences were:

  • headache — 15% of tested men;
  • stomach upset — 10% of patients;
  • ache in back — 6% of men;
  • pain in muscles — 3%;
  • painful limbs — 3%;
  • flushing — 3%;
  • infections of the upper respiratory tract, stuffy nose — 3%;
  • diarrhea was noticed only in 2,5% of men, and mostly older than 65 years old;
  • changing color perception were very rare — less than on 0.5% of cases.

There are some other side effects revealed while clinical testing, but they are rare (less than 2%) and are more connected to the state of overall health:

  • body: fatigue, weakness, swelling;
  • cardiovascular system: stenocardia, pain in chest, low blood pressure, tachycardia, fast heartbeat, cardiac infarction;
  • digestive system: liver disorders, dry mouth, difficulty swallowing, esophagitis, gastritis, increased level of gamma-glutamyl transferase, nausea, vomiting, rectal hemorrhage;
  • musculoskeletal system: pain in joints and neck;
  • nervous system: lightheadedness, insomnia, dizziness, numbness, abnormal dermal sensation;
  • skin: itching, rash, sweating;
  • kidney insufficiency;
  • respiratory system: shortness of breath, nosebleeds, pharyngitis;
  • eyes: blurred vision, pink eye, epiphora, eye swelling, painful eyes;
  • ears: sonitus, sudden decrease or loss of hearing;
  • genitourinary system: abnormal or uncontrolled erection.

Most adverse reactions are not serious and disappear with the next Cialis intake. You have to be cautious if these side effects don’t leave. If you feel bad or have severe trouble, immediately call the doctor. In the risk group there are people who are older 50 years old, smokers, having cardiovascular diseases, diabettis, high cholesterol level, low or high blood pressure, blood diseases like mieloma, anemia, hemophilia, blood cancer, kidney and liver disorders, recent stroke, gastric ulcer, retinitis pigmentosa, severe penis deformation, and all the diseases when sex is not recommended. Never take Cialis without your health provider’s consultation if you have at least one of those conditions.

Interactions

You shouldn’t take Cialis together with:

  • nitrates (they treat pain in the chest, for instance nitroglycerin, isosorbide, etc.), because Cialis enhances their action. It must pass not less than 48 hours after the dose of Cialis to be able to use nitrates medications;
  • alpha-blockers (drugs for enlarged prostate, prostate adenoma, hypertonia, e.g. tamsulosin, doxazosin, and so on), because they both lower blood pressure, which can lead to the collapse;
  • antihypertensives (high blood pressure medications, for example enalapril, amlodipine, etc.), as they also can decrease blood pressure critically when cooperating together;
  • alcohol has vasodilation effect, and big amount of it (more than five drinks) together with tadalafil can lead to headache, fasten heartbeat, vertigo, decrease of blood pressure;
  • antacids can reduce absorbing tadalafil in the blood;
  • some CYP3A4 inhibitors, such as ketoconazole, erythromycin, itraconazole, and grapefruit juice increase tadalafil action in the body;
  • anti-HIV drugs also are not recommended to use together with Cialis for the same reason — they increase its action and lead to severe negative consequences.

Where to Buy Legally and Securely

In the USA the patent on brand Cialis belongs to Eli Lilly and Co, and if you want to get the drug, you will need to have the doctor’s prescription and a wallet full of money. If you have both things, you’re lucky and don’t hesitate anymore to go to a drug store. Another alternative is generic version, that you can buy via Internet. 

Online retailers are not forbidden in the USA, and generic Cialis, which is mostly produced in India and approved by the state, has the same effect and quality. All the matter about price difference is the patent. So, why to pay more? 

In our online pharmacy you will find generic Cialis 20 mg for the best price. You will see the changes in your life even after the first dose and will forget about the problem with ED forever. You will be surprised by our flexible price policy, bonus and discount system, quick delivery, which will be absolutely free for the orders above 200 USD. 

You can choose the way of payment, which is convenient specially for you: we accept Bitcoins, debit and credit cards. You can buy your Cialis without the prescription and fully anonymously. We respect our clients and guarantee quality, safety and reliability. Don’t doubt anymore, your future is in your hands!